产品货号:
Z37414
中文名称:
IRF2抗体
英文名称:
Anti-IRF2 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-IRF2 Antibody |
指标别名 | IRF 2;IRF2 |
克隆性 | Monoclonal |
检验物种 | human,mouse |
应用范围 | WB,IHC,ICC/IF |
基因名称 | IRF2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human IRF2 |
实际分子量 | 50KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | IRF2 (interferon regulatory factor 2) is a member of the interferon regulatory transcription factor (IRF) family.The IRF2 gene is mapped on 4q35.1.When the IRF2 gene was overexpressed in NIH 3T3 cells,the cells became transformed and displayed enhanced tumorigenicity in nude mice.One IRF binding site was found within the IRF2 promoter,and expression of the IRF2 gene was affected by both transient and stable IRF1 expression.IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta,and presumably other genes that employ IRF1 for transcription activation.However,IRF2 also functions as a transcriptional activator of histone H4.Irf2 was required to prevent NK-cell apoptosis and keep immature NK cells alive,thus promoting NK-cell maturation and their supply to peripheral blood. |
Uniprot ID | P14316 |
基因名全称 | Interferon regulatory factor 2 |
推荐稀释比 | Western blot (WB) 1:400~800 Immunohistochemistry in paraffin section (IHC) 1:20~100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100 |
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